Monday, November 28, 2011

'Left-handed iron corkscrews' point the way to new weapon in battle against superbugs like MRSA

'Left-handed iron corkscrews' point the way to new weapon in battle against superbugs like MRSA [ Back to EurekAlert! ] Public release date: 27-Nov-2011
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Contact: Anna Blackaby
a.blackaby@warwick.ac.uk
44-247-657-5910
University of Warwick

Scientists at the University of Warwick have taken inspiration from corkscrew structures found in nature to develop a new weapon in the fight against infections like E-coli and MRSA.

Researchers have created a new synthetic class of helix-shaped molecules which they believe could be a key tool in the worldwide battle against antibiotic resistance.

By twisting molecules around iron atoms they have created what they term 'flexicates' which are active against MRSA and E-coli - but which also appear to have low toxicity, reducing the potential for side effects if used in treatment.

The work is published in Nature Chemistry.

The new structures harness the phenomenon of 'chirality' or 'handedness' whereby the corkscrew molecules could be left-handed or right-handed.

By making the most effective 'hand' to attack a specific disease, the University of Warwick research paves the way towards a more targeted approach to killing pathogens.

In the case of E-coli and MRSA, it is the left 'hand' which is most effective.

Professor Peter Scott of the University of Warwick's chemistry department said although this particular study concentrated on flexicates' activity against MRSA and E-coli, the new method of assembly could also result in new treatments for other diseases.

"It's a whole new area of chemistry that really opens up the landscape to other practical uses.

"These new molecules are synthetically flexible, which means that with a bit of tweaking they can be put to use against a whole host of different diseases, not just bugs like MRSA which are rapidly developing resistance to traditional antibiotics.

"Flexicates are also easier to make and produce less waste than many current antibiotics."

Scientists have long been able to copy nature's corkscrew-shaped molecules in man-made structures known as helicates but they have thus far not been able to use them in fighting diseases.

One of the key issues is the problem of handedness.

Sometimes 'left-handed' molecules in drugs are the most effective at combating some disease, while sometimes the 'right-handed' version works best.

Until now, scientists working with helicates have found it difficult to make samples containing just one type of corkscrew; either the right- or left-handed twist.

But with flexicates, the University of Warwick scientists have succeeded in making samples containing just one type of twist resulting in a more targeted approach which would allow the drug dosage to be halved.

And flexicates solve other problems encountered by helicates, as they are easier to optimise for specific purposes, are better absorbed by the body and are also easier to mass-produce synthetically.

Professor Scott said: "Drugs often have this property of handedness - their molecules can exist in both right and left handed versions but the body prefers to use only one of them."

"For this reason, drug companies have to go to the trouble of making many traditional molecules as one hand only.

"What we have done is solve the 'handedness' problem for this new type of drug molecule.

"By getting the correct hand we can halve the drug dose, which has the benefits of minimising side effects and reducing waste.

"For patients, it's safer to swallow half the amount of a drug.

"Our work means that we can now make whichever hand of the corkscrew we want, depending on the job we require it to do."

###

Notes to editors

The study, entitled Optically pure, water-stable metallo-helical 'flexicate' assemblies with antibiotic activity, is published in Nature Chemistry.

The research was also supported financially by EPSRC.

It is authored by Peter Scott, Suzanne Howson, Guy Clarkson and Alison Rodger from the University of Warwick, Albert Bolhuis from the University of Bath and Viktor Brabec and Jaroslav Malina from the Academy of Sciences of the Czech Republic.

When the paper is published it can be retrieved at http://dx.doi.org/10.1038/NCHEM.1206

Contact details

Professor Peter Scott is available on +44 (0) 24 7652 3238 or +44 (0) 7799 227071 or peter.scott@warwick.ac.uk

University of Warwick press officer Anna Blackaby is available on + 44 (0) 2476 575910 or + 44 (0)7785 433155 or a.blackaby@warwick.ac.uk


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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


'Left-handed iron corkscrews' point the way to new weapon in battle against superbugs like MRSA [ Back to EurekAlert! ] Public release date: 27-Nov-2011
[ | E-mail | Share Share ]

Contact: Anna Blackaby
a.blackaby@warwick.ac.uk
44-247-657-5910
University of Warwick

Scientists at the University of Warwick have taken inspiration from corkscrew structures found in nature to develop a new weapon in the fight against infections like E-coli and MRSA.

Researchers have created a new synthetic class of helix-shaped molecules which they believe could be a key tool in the worldwide battle against antibiotic resistance.

By twisting molecules around iron atoms they have created what they term 'flexicates' which are active against MRSA and E-coli - but which also appear to have low toxicity, reducing the potential for side effects if used in treatment.

The work is published in Nature Chemistry.

The new structures harness the phenomenon of 'chirality' or 'handedness' whereby the corkscrew molecules could be left-handed or right-handed.

By making the most effective 'hand' to attack a specific disease, the University of Warwick research paves the way towards a more targeted approach to killing pathogens.

In the case of E-coli and MRSA, it is the left 'hand' which is most effective.

Professor Peter Scott of the University of Warwick's chemistry department said although this particular study concentrated on flexicates' activity against MRSA and E-coli, the new method of assembly could also result in new treatments for other diseases.

"It's a whole new area of chemistry that really opens up the landscape to other practical uses.

"These new molecules are synthetically flexible, which means that with a bit of tweaking they can be put to use against a whole host of different diseases, not just bugs like MRSA which are rapidly developing resistance to traditional antibiotics.

"Flexicates are also easier to make and produce less waste than many current antibiotics."

Scientists have long been able to copy nature's corkscrew-shaped molecules in man-made structures known as helicates but they have thus far not been able to use them in fighting diseases.

One of the key issues is the problem of handedness.

Sometimes 'left-handed' molecules in drugs are the most effective at combating some disease, while sometimes the 'right-handed' version works best.

Until now, scientists working with helicates have found it difficult to make samples containing just one type of corkscrew; either the right- or left-handed twist.

But with flexicates, the University of Warwick scientists have succeeded in making samples containing just one type of twist resulting in a more targeted approach which would allow the drug dosage to be halved.

And flexicates solve other problems encountered by helicates, as they are easier to optimise for specific purposes, are better absorbed by the body and are also easier to mass-produce synthetically.

Professor Scott said: "Drugs often have this property of handedness - their molecules can exist in both right and left handed versions but the body prefers to use only one of them."

"For this reason, drug companies have to go to the trouble of making many traditional molecules as one hand only.

"What we have done is solve the 'handedness' problem for this new type of drug molecule.

"By getting the correct hand we can halve the drug dose, which has the benefits of minimising side effects and reducing waste.

"For patients, it's safer to swallow half the amount of a drug.

"Our work means that we can now make whichever hand of the corkscrew we want, depending on the job we require it to do."

###

Notes to editors

The study, entitled Optically pure, water-stable metallo-helical 'flexicate' assemblies with antibiotic activity, is published in Nature Chemistry.

The research was also supported financially by EPSRC.

It is authored by Peter Scott, Suzanne Howson, Guy Clarkson and Alison Rodger from the University of Warwick, Albert Bolhuis from the University of Bath and Viktor Brabec and Jaroslav Malina from the Academy of Sciences of the Czech Republic.

When the paper is published it can be retrieved at http://dx.doi.org/10.1038/NCHEM.1206

Contact details

Professor Peter Scott is available on +44 (0) 24 7652 3238 or +44 (0) 7799 227071 or peter.scott@warwick.ac.uk

University of Warwick press officer Anna Blackaby is available on + 44 (0) 2476 575910 or + 44 (0)7785 433155 or a.blackaby@warwick.ac.uk


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2011-11/uow-ic112411.php

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Raising Cain: How a poor Georgia boy succeeded in business, and aimed for the presidency (Star Tribune)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories News, RSS and RSS Feed via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/166714895?client_source=feed&format=rss

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US ranchers: We live in fear along Mexican border

While walking along a dirt road bordering his property, a South Texas farmer complained about living in fear of Mexican traffickers smuggling drugs and illegal immigrants across his land. He would later ask his visitor not to reveal his identity, for his safety and that of his family.

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"I'm a citizen of the United States. This is supposedly sovereign soil, but right now it's anybody's who happens to be crossing here," he said. "I'm a little nervous being here right now. Definitely don?t come down here after dark."

The farmer said a federal law enforcement agent told him to buy a bulletproof vest to use while working in his fields. Whenever he goes out to survey his agricultural operations, he always tells his office where he is headed, and he has purchased a high-powered rifle.

"One of the basic points of the federal government is to protect the people of this nation to secure the border, and they're not doing that," he complained.

Story: Cartels using Ariz. mountaintops to spy on cops

The Obama administration and many local officials have said the U.S.-Mexican border is safer than ever and that reports of violence on the American side are wildly exaggerated. But the farmer scoffed at that argument. "I walk this soil every day and have since I was old enough to come out on my own," he said. "In this part of Texas, it is worse than it's ever been."

Moving families to safer ground
A report recently released by the Texas commissioner of agriculture said cross-border violence was escalating. "Fear and anxiety levels among Texas farmers and ranchers have grown enormously during the past two years," the report said, adding that some ?have even abandoned their livelihoods to move their families to safer ground."

Retired U.S. Army Gen. Barry McCaffrey, who served as the U.S. drug czar during the Clinton administration and as an NBC News military analyst, is a co-author of the report. During a recent interview, McCaffrey said that while major cities along the Texas border are "pretty safe," the rural areas between towns are "largely unprotected, and across those areas the (Mexican) cartels are conducting massive movements of illegal drugs and other criminal activity."

Story: Mexican cartels corrupting more US border officials?

Law enforcement agents say they are seeing more aggressive efforts by Mexican traffickers operating in the Rio Grande Valley. In South Texas alone, the traffickers smuggle hundreds of tons of drugs a year into the United States by floating them on rafts across the Rio Grande, then transporting them by car, truck or on foot ? often across private land ? into the United States.

Video: 'Like living in a war zone' (on this page)

The smuggling ?clearly has intimidated U.S. citizen who don't believe they're safe on their own land in their own country," McCaffrey said.

Several Texas congressmen and sheriffs have condemned the report, saying its conclusions are overstated and politically driven. But McCaffrey claims the officials not facing facts.

"I think there is an element of denial," McCaffrey said. "Inside the beltway the senior law enforcement, I think, have fallen in line and said, no, that's right, the U.S. border is the safest place in America, which is errant nonsense."

Ranchers protecting themselves
Veterinarian and rancher Mike Vickers heads the Texas Border Volunteers, a group of about 300 landowners and supporters who work closely with law enforcement officials to track drug and immigrant smugglers entering the U.S. from Mexico and crossing private land. His primary concern, he said, is the safety of farmers and ranchers who have been confronted by armed traffickers.

"A lot of them have been threatened not to call the Border Patrol or law enforcement if they see smuggling going on their property, otherwise they'll be killed or their family members may be killed," he said.

Video: 'It's compromised our lives' (on this page)

During a tour of his land and that of a neighbor, Vickers pointed out numerous hiking trails worn by smugglers and illegal immigrants from around the world. He also showed where many parts of the wire fence had been cut and pulled back. "This is not done by wildlife," he said. "This is done by smugglers and more than likely drug smugglers that have heavy backpacks full of drugs so they can drag the backpack underneath and not have to throw it over the fence."

In order to prove their claims that thousands of smugglers and illegal immigrants are crossing private American land, the Texas Border Volunteers have erected hidden cameras and share the images with state and federal agents. Describing one of the pictures, Vickers said, "This individual's got at least 80, maybe 100 pounds on his back. This is probably marijuana with a canvas covering." Another black and white photograph showed a man hoisting a smaller load. "You know he's carrying at least 40 pounds of drugs in that backpack. We suspect cocaine."

Video: Drug flow from Mexico on the rise

Vickers said that since 2004, about 500 people, mostly illegal immigrants, have perished while on smuggling trips through private property in Brooks County, Texas, alone, where his ranch is located.

A war zone?
Todd Staples, the Texas agriculture commissioner and a candidate for lieutenant governor, argued that many leaders in Washington, D.C., continue to ignore the violence along the border. In a recent article he wrote, "A Webb County rancher checking his cattle is shot at and barely escapes with his life; the suspects are linked to drug cartels. Workers in a Hidalgo County sugarcane field are told by cartel members to stop harvesting the crop 'or else," because the sugarcane provides coverage for cartel coyotes smuggling drugs."

Vickers said he knows ranchers who have moved their families into nearby cities for their protection and have taken other safety measures. "Everyone is packing a weapon and carrying a cell phone with them. and they're crazy if they don't," he said. "This is happening on American soil; this is a war zone here, there's no question about it."

The use of the phrase "war zone" to describe the U.S. side of the border is controversial. The report to the agriculture commissioner states, "Living and conducting business in a Texas border county is tantamount to living in a war zone in which civil authorities, law enforcement agencies as well as citizens are under attack around the clock."

Video: Drug violence comes to Mexican resort (on this page)

Democratic congressmen and some local officials say that conclusion is unfair. Hidalgo County Sheriff Lupe Trevino was recently quoted by the Houston Chronicle as saying, "The border is not in chaos.? And the newspaper quoted Rep. Silvestre Reyes, a Democrat representing El Paso, as calling the claims "political rhetoric" meant to embarrass the Obama administration.

Among ranchers, farmers and law enforcement agents working at the ground level, however, there is considerable agreement that large-scale drug smuggling from Mexico into the United States has been increasing in recent years and that the traffickers are becoming more aggressive. For the farmer too afraid to be identified publicly, it creates a painful dilemma.

"I can't pick up and move this farm; we're tied to the land," he said. "This is the front door to our country. Help us stop it here."

? 2010 msnbc.com? Reprints

Source: http://www.msnbc.msn.com/id/45440385/ns/nightly_news/

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Looking to build, Gingrich eyes South Carolina (AP)

WASHINGTON ? Republican presidential contender Newt Gingrich looked to turn an endorsement from New Hampshire's largest newspaper into momentum elsewhere, heading to South Carolina for a three-day campaign swing with tea party members.

His leading rival, former Massachusetts Gov. Mitt Romney, did not schedule campaign appearances on Monday, but his advisers were working to downplay The New Hampshire Union Leader's backing of Gingrich in Romney's back yard. The newspaper's rejection of Romney, who enjoys solid polling leads in that state and has worked to line up activists, stood to potentially reshape the entire campaign.

"We don't back candidates based on popularity polls or big-shot backers. We look for conservatives of courage and conviction who are independent-minded, grounded in their core beliefs about this nation and its people, and best equipped for the job," the newspaper said in its Sunday front-page editorial.

The Union Leader's editorial is a sign that conservative concerns about Romney's shifts on crucial issues of abortion and gay rights were unlikely to fade. Those worries have led Romney to keep Iowa's Jan. 3 caucuses ? where conservatives hold great sway ? at arm's length.

At the same time, the endorsement boosts Gingrich's conservative credentials. He spent the week defending his immigration policies against accusations they represent a form of amnesty. On Monday, Gingrich was to begin a campaign swing through South Carolina, the South's first primary state. There, he will have a town hall meeting with Rep. Tim Scott and tea party activists in Charleston.

Romney, taking a few days' break for the Thanksgiving holiday, has kept focused on a long-term strategy that doesn't lurch from one development to another. Last week, he picked up the backing of Sen. John Thune, a South Dakota conservative, to add to his roster of supporters.

Romney planned to return to the campaign on Tuesday in Florida.

The Union Leader's rejection of Romney wasn't surprising despite his efforts to woo state leaders. The newspaper rejected Romney four years ago in favor of Arizona Sen. John McCain, using front-page columns and editorials to promote McCain and criticize Romney.

Romney, the former Massachusetts governor who has a vacation home in the state and has been called a "nearly native son of New Hampshire," absorbed the blow heading into the Jan. 10 vote that's vital to his campaign strategy.

Yet with six weeks until the primary, The Union Leader's move could again shuffle the race, further boosting Gingrich and driving a steady stream of criticism against his rivals. In recent weeks, the former House speaker has seen a surge in some polls as Republicans focus more closely on deciding who they consider best positioned to take on President Barack Obama.

Source: http://us.rd.yahoo.com/dailynews/rss/gop/*http%3A//news.yahoo.com/s/ap/20111128/ap_on_el_pr/us_campaign2012

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Sunday, November 27, 2011

Racism's Mental Toll May Explain Some Health Disparities (HealthDay)

FRIDAY, Nov. 25 (HealthDay News) -- Racism is similar to trauma in how it affects the mental health of black adults in the United States, a new analysis finds.

An examination of 66 previous studies that included more than 18,000 black adults concluded that there are common responses to both racism and trauma, including somatization (psychological distress that is expressed as physical pain), interpersonal sensitivity and anxiety. The more stressful the racism, the more likely a person was to report mental distress.

The study is published online in the Journal of Counseling Psychology.

The researchers suggested that the link between mental health and racism could contribute to physical health disparities between blacks and other Americans of different races and ethnicities.

"The relationship between perceived racism and self-reported depression and anxiety is quite robust, providing a reminder that experiences of racism may play an important role in the health disparities phenomenon," study lead author Alex Pieterse from the University at Albany, State University of New York, said in an American Psychological Association news release. "For example, African Americans have higher rates of hypertension [high blood pressure], a serious condition that has been associated with stress and depression."

The study's authors noted that therapists should routinely assess their black patients' experiences with racism during treatment.

More information

The U.S. Centers for Disease Control and Prevention has more on health disparities related to race and ethnicity.

Source: http://us.rd.yahoo.com/dailynews/rss/diseases/*http%3A//news.yahoo.com/s/hsn/20111126/hl_hsn/racismsmentaltollmayexplainsomehealthdisparities

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Akamai Reportedly Buying Rival Cotendo For Up To $350 Million

cotendoClassify this as a rumor for now, but Israeli business press is reporting that Akamai is poised to take over one of its competitors, website and mobile acceleration technology vendor Cotendo, for $300 million to $350 million. Founded in 2008, Cotendo has raised over $36 million in funding from investors like Sequoia Capital, Benchmark Capital and Tenaya Capital. A few months ago, Cotendo raised $17 million in new funding from its previous backers, with Citrix Systems and Juniper Networks stepping in as strategic investors as well.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/RzneMXv8wec/

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Saturday, November 26, 2011

Thanksgiving Food Waste Reduction Tips (PHOTOS)

Before the meal: Plan your menu and exactly how much food you'll need. The fear of not providing enough to eat often causes hosts to cook too much. Instead, plan out how much food you and your guests will realistically need, and stock up accordingly. The Love Food Hate Waste organization, which focuses on sharing convenient tips for reducing food waste, provides a handy "Perfect portions" planner to calculate meal sizes for parties as well as everyday meals.

Source: http://www.huffingtonpost.com/2011/11/24/reducing-thanksgiving-food-waste_n_1110819.html

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Suh says actions 'unacceptable' (AP)

DETROIT ? For the first season-and-a-half of his young career, Ndamukong Suh could almost brush off talk about his penalties and fines, saying he would keep doing what was needed to help his Detroit Lions.

After hurting the team with a penalty and ejection on Thanksgiving, Suh now says he has learned his lesson.

"My reaction on Thursday was unacceptable," the star defensive tackle said in a statement on his Facebook page Friday night. "I made a mistake, and have learned from it. I hope to direct the focus back to the task at hand ? by winning."

The statement appeared on Suh's page around the same time he was publically chastised by the Lions, one night after being ejected Thursday in a loss to Green Bay for stomping at an opposing player.

"The on-field conduct exhibited by Ndamukong Suh that led to his ejection from yesterday's game was unacceptable and failed to meet the high level of sportsmanship we expect from our players," the team said. "Ndamukong has made many positive contributions to the Lions on and off the field. We expect his behavior going forward to consistently reflect that high standard of professionalism."

It could be several days before Suh finds out the true cost of his third-quarter stomp in Detroit's 27-15 loss to the Packers on Thursday. An NFL spokesman said Friday that plays from Week 12 looked at for potential discipline won't be reviewed until all games are completed.

Detroit coach Jim Schwartz was curt after Thursday's defeat when asked if he was worried about a possible suspension.

"I'm worried about losing this game," Schwartz said.

Suh was dismissed after tangling with Packers offensive lineman Evan Dietrich-Smith. After being pushed off Dietrich-Smith, Suh stepped down hard with his right foot, appearing to make contact with Dietrich-Smith's right arm.

Immediately after the game, Suh defended himself, saying he was trying to keep his balance while freeing himself from the brief scuffle. He publically apologized to teammates, coaches and fans Thursday for "allowing the refs to have an opportunity to take me out of this game," but he insisted he didn't intentionally step on anyone.

"People are going to have their own opinions ? that's fine," he said after the game. "The only (people) that I really care about are my teammates, my true fans and my coaches and their opinions, and that's where it lies. And honestly, the most important person in this whole thing that I have to deal with is the man upstairs."

In his Friday statement on Facebook, he said he'd had more time to reflect.

"Playing professional sports is not a game," he said. "It is a profession with great responsibility, and where performance on and off the field should never be compromised. It requires a calm and determined demeanor, which cannot be derailed by the game, referee calls, fans or other players."

In less than two seasons as a pro, Suh has established himself as one of the game's strongest and most athletic defensive linemen, but he's also received his share of fines.

Suh requested and received a meeting earlier this month with Commissioner Roger Goodell to discuss his play. He said that dialogue was helpful, but now the league will have to decide whether more discipline is merited after he was ejected on national television.

New York Jets coach Rex Ryan came up with one tongue-in-cheek solution Friday.

"I'll be honest with you, I think the young man, he should be released ... and come to the Jets," Ryan joked. "I'm just throwing that out there. I don't think he's that good of a player. I don't know about the incident and all that jazz, but we'll take him. We'll sacrifice that way."

Ryan then turned a little more serious.

"I don't even know what to say on it," Ryan said. "You've seen things like that happen on the field before. It's an emotional game."

Jets offensive lineman Matt Slauson, who played with Suh at Nebraska, sounded off on the topic Friday.

"Somebody needs to get him under control, because he's trying to hurt people," Slauson told the New York Post. "It's one thing to be an incredibly physical player and a tenacious player, but it's another thing to set out to end that guy's career."

Slauson said last year that he and Suh used to mix it up in practice while in college.

"There were times we got into fights, during spring ball, during camp, but I kind of fought everyone," Slauson said then.

In 2006, Albert Haynesworth, then with the Tennessee Titans, was suspended five games after swiping his cleats across the head of helmetless Dallas center Andre Gurode. Suh's stomp wasn't toward Dietrich-Smith's head, and the Green Bay player didn't seem too much worse for wear.

When asked afterward where Suh stepped on him, Dietrich-Smith sounded like he didn't want to stir the pot.

"I have no idea," he said. "I have to watch the tape."

If Suh is suspended early next week, he would have a chance to keep playing pending any appeal ? but that appeals process can be expedited. Detroit plays at New Orleans on Dec. 4.

The NFL moved that game to prime time, a reflection of the buzz surrounding the improved Lions this season. Led by young stars Suh, Matthew Stafford and Calvin Johnson, Detroit won its first five games, but the Lions have since lost four of six.

Defensive backs Louis Delmas, Chris Houston and Brandon McDonald went down with injuries against the Packers, and so did running back Kevin Smith. If the Lions are without Suh for an extended period, it could hurt them in the playoff race.

"He plays aggressive. All of us, sometimes, might overreact in certain situations," Detroit defensive lineman Cliff Avril said. "We've got to play real smart."

___

AP Sports Writer Dennis Waszak Jr., in Florham Park, N.J., contributed to this report.

Source: http://us.rd.yahoo.com/dailynews/rss/sports/*http%3A//news.yahoo.com/s/ap/20111126/ap_on_sp_fo_ne/fbn_suh_s_stomp

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AT&T, Telekom to press ahead with T-Mobile deal

Deutsche Telekom and AT&T vowed Thursday to press ahead with the planned sale of the German company's T-Mobile USA unit to the U.S. cell phone operator despite concerns raised by American authorities.

Nevertheless, AT&T said it plans to take a pretax accounting charge of $4 billion in the current quarter to reflect the break-up fees that would be due to Deutsche Telekom if regulators block the deal.

The two companies said they had withdrawn applications to the Federal Communications Commission regarding the merger and intended to seek its approval again "as soon as practical."

They took the step to consider "all options at the FCC and to focus their continuing efforts on obtaining antitrust clearance for the transaction from the Department of Justice," which filed a lawsuit in August to stop the deal, AT&T said in a statement.

"Both companies are continuing to pursue the sale of T-Mobile USA to AT&T," Deutsche Telekom stressed.

Both U.S. agencies worry that the deal would hamper competition and lead to higher prices for consumers.

Deutsche Telekom AG and AT&T Inc. made their move after the chairman of the FCC earlier this week came out against the merger.

Julius Genachowski made his position known in a document he circulated to fellow commissioners Tuesday.

He recommended sending AT&T's proposed $39 billion takeover of T-Mobile to an administrative law judge for review and a hearing. That's what the FCC does when it opposes a merger.

In a research note Thursday, Jefferies International analyst Ulrich Rathe said the withdrawal of the FCC application, as well as the opposition by the Justice Department, indicate that "the companies are already well into working out a new version of the deal."

The analyst, who rates Deutsche Telekom "Buy," said the charge confirms the break-up fee will be difficult for AT&T to avoid if the deal is not completed.

In Frankfurt, Deutsche Telekom shares closed down 0.6 percent Thursday at euro8.69 ($11.67), almost mirroring the 0.5 percent decline in the DAX index of blue-chip stocks.

The proposed deal, announced in March, would vault the combination of America's No. 2 carrier AT&T and No. 4 T-Mobile into the top spot ahead of Verizon.

Dallas-based AT&T has about 101 million wireless subscribers. T-Mobile, the Bellevue, Washington-based subsidiary of Deutsche Telekom AG of Germany, has 34 million.

Verizon Wireless, a joint venture between Verizon Communications Inc. and Vodafone Group PLC, has about 108 million, while Sprint Nextel Corp. has 53 million.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2011-11-25-US-ATandT-T-Mobile/id-9051e482596a4df19b300227ca33cb13

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Auto Fx Investing You Must Know This! | Watch My Gear

Auto foreign exchange buying and selling, automates the currency or trading market that will take spot at the international exchange it is commonly identified as the foreign exchange, fx or forex exchange. Present day international exchange market, is the end result of a transformation that took place thirty a long time ago, when a floating exchange fee grew to become much more prevalent. The fx marketplace has a every day world wide trade, that is nicely in the trillions of bucks and entails the large banks and firms, governments and speculators. This market facilitates trade and investment, by enabling the exchange of currencies this kind of as the Pound sterling, US greenback or Canadian dollar.

Is This Market- Distinctive?

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Source: http://watchmygear.com/2011/auto-fx-investing-you-must-know-this/

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Friday, November 25, 2011

Reviews: Box sets from U2, Pink Floyd, Sting, more (AP)

Here are The Associated Press' reviews of selected box sets released this year:

U2, "Achtung Baby," Super Deluxe Edition Box Set (Island/Interscope/UMe)

Longevity in the music business can be traced to a pivotal moment in an artist's career, and for U2, that milestone was "Achtung Baby." The seminal 1991 album represented U2 2.0, the point where the band reinvented itself. Now fans can experience the making of the classic recording with a box set that includes nearly as many discs as album releases.

The album that spawned such classics as "One" and "Mysterious Ways" was recorded in Berlin during a tumultuous period for the band.

After experiencing the mega-success of "The Joshua Tree" and the concert film "Rattle and Hum," the band was at a crossroads. So they broke away from their families to find their sound in a distant land.

But things didn't go as planned. Disagreements over musical direction weighed heavy on the band and divisions formed. Bono and the Edge wanted to move toward an electronic sound, while Larry Mullen and Adam Clayton yeaned for a classic rock sound. And producer Daniel Lanois wanted to recapture the tone of past recordings.

After a great deal of tension, they found what they were looking for with "One," and the rest fell into place. Not only were they able to churn out the remainder of the album, but they also recorded the follow-up, "Zooropa."

The trajectory of "Achtung Baby" shares similarities to Bruce Springsteen's "Darkness on the Edge of Town" and the ensuing documentary, "The Promise," as being pivotal by showing growth in the music. Like the "Darkness" album, U2 gets a feature-length documentary chronicling the pain-staking process in Davis Guggenheim's "From the Sky Down."

The entire history of "Achtung Baby" is chronicled in the super deluxe edition. It consists of six compact discs and four DVDs, including the documentary, and a Zoo TV special. Other goodies in the box include a hardcover book and 16 art prints.

Fans of the band are treated to the original album, and a variety of extra material that ranges from informative to overkill, depending on your level of fandom. Still, there's a little too much raw material here for most listeners to process. And besides, who really needs to see four different versions of the video for "One"?

There's a scaled-down two disc set that includes 14 additional tracks, as well as an uber-deluxe version at the uber-high price of $434.99 that includes a set of collectible vinyl singles, a magnetic puzzle tiled box, and a pair of Bono's trademark "Fly" sunglasses.

? John Carucci, Associated Press

___

Nirvana, "Nevermind Super Deluxe Edition" (Geffen)

Working through the hours of material on this 20th anniversary celebration of Nirvana's atom bomb of an album, "Nevermind," is an unexpectedly melancholy experience.

The music here is just as vital as it was the day it knocked Michael Jackson from the top of the charts ? perhaps even more so, given that time as failed to produce a worthy successor.

When "Nevermind" hit the street in 1991, destroying hair metal in just a few bars of "Smells Like Teen Spirit," it reshaped not just rock music but pop and punk and America. It captured a moment, the aimless uneasiness of a large part of a generation, and heralded the promise of something better.

As Cobain noted announcing the arrival of "Nevermind," "Punk is musical freedom."

And it was ? for a moment. What "Nevermind" reminds us is that freedom was quickly commodified and corporatized. Everyone sought to copy the magic formula that Kurt Cobain and Co. used to erase years of malaise in American rock `n' roll.

Listening to the various versions of "Nevermind" in this edition, one of two commemorative releases, reminds us that no one's really come close to carrying the standard in the years after Nirvana's fiery flare across the night sky. And that's pretty disheartening.

The super deluxe version is both fascinatingly deep and needlessly so at the same time. There are four discs with 69 cuts that include a remastered version of the original album, various B-sides, live cuts and unreleased versions and even a few early boom box proto-recordings that provide a glimpse at the evolution of Nirvana's biggest hits. There's also a book that includes photos and other artifacts from the period (For those curious but looking for something a little more economical, there's also a 39-song, two-disc version that's a fraction of the cost).

The highlight of the super deluxe edition is the "Nirvana: Live at the Paramount" DVD of the band's Oct. 31, 1991, concert in Seattle. Things were just starting to blow up and the band is lean and powerful and young and beautiful, and there's no hint of things to come.

It's a moment in time that's nearly perfect.

? Chris Talbott, AP Entertainment Writer

___

The Smiths, "The Smiths Complete" (Rhino)

Everybody's got one in their life. That kid ? a nephew or daughter or neighbor ? who's alone in a crowded room, gloomy on a sunny day, a wardrobe leaning toward black coats and heavy eyeliner.

We have the perfect Christmas gift for that kid (even if she hates Christmas): "The Smiths Complete." It's a swank box set, in both CD and vinyl, containing all four studio albums released in an astounding flurry between 1984 and 1987 and four more discs of live bits and odds and ends.

Morrissey's sweetly crooned rancor and cutting indignation remain a soothing balm all these years later, and Johnny Marr's diamond-lattice guitar work is still every bit as engaging as it was in the mid-1980s, despite all the copycats and pretenders over the years.

These albums were grenades lobbed at the establishment at the time and should find fresh ears in the 21st century. Morrissey and his mates were reacting to the growing elitism of the wealthy and the many inequalities of modern society. Many of the same themes have re-emerged 25 years later in the age of Occupy Wall Street and open class warfare.

The Smiths have aged very well. "The Queen is Dead" and "Vicar in a Tutu" remain vibrant and alive, the sneer still fresh on the lips. "There is a Light That Never Goes Out" and "I Want the One I Can't Have" remain just as heartbreakingly sad. And songs like "How Soon is Now" and "London" still rock with an unexpected ferocity.

The one disappointment is the light liner notes. But what's here gives us a starting point, and Morrissey takes it from there.

? Chris Talbott, AP Entertainment Writer

____

Pink Floyd, "The Dark Side of the Moon Immersion" (Capitol Records)

Regarded as one of the most important albums in pop thanks to its unprecedented life on the charts and timeless sound, it should come as no surprise the iconic album "The Dark Side of the Moon" gets the box set treatment.

"The Immersion Collection," as it's called, consists of six discs centered on the album, and lots of collectibles, including a 40-page booklet, marbles, drink coasters, and a scarf. That's right, a scarf, complete with the album's trademark dispersive prism.

While these items may be cool for a few minutes, the real value of this collection lies in the album's original mix, which up until now, has never been released. Unlike alternate takes that seem to pervade these types of collections, the early mix of this album stands on its own merit. Presented in its entirety, it provides a different perspective of the version of the album burned into our minds over the past 37 years.

"Dark Side" seemed to culminate the experimental soundscape of the band's seven previous albums with the right blend of mainstream appeal. So this cut of the album serves as the step before their masterpiece was complete.

Roger Waters wrote the album about a daily stresses of living, and David Gilmour sings most of the songs on the album with the exception of the final two, "Brain Damage," and "Eclipse," which were sung by Waters. The album marked a major change for the band as they went from a psychedelic rock band to rock `n' roll history. It stayed in the Top 200 for a record 741 weeks.

If you ever wondered what "Great Gig in the Sky" would sound like without Claire Torry's non-lexical vocals, or a different maniacal laugh on "Brain Damage," then you'll get to hear those versions and much more.

There's even an instrumental of "Us and Them," which was the song's earliest version. "The Violent Sequence," as it was originally titled, was written by keyboardist Richard Wright for the Michelangelo Antonioni film, "Zabriskie Point." The director rejected the track, and it found new life with Roger Waters' haunting lyrics.

Another track, "The Travel Sequence," was a piece the band did in concert since 1970. For "Dark Side," it would eventually evolve into "On the Run." For fans of the album, this disc, along with an included 2003 documentary on the making of the album, is a history lesson.

? John Carucci, Associated Press

___

Billy Joel, "Billy Joel: The Complete Albums Collection" (Columbia/Legacy)

We live in a fragmentary culture. Songs are "quoted" in commercials, sampled in other songs, heard in slivers in all corners of our landscapes.

How odd, then, to be able to listen to the entire arc of a singer-songwriter's artistic life in one package ? and see, as close as is possible in art, the complete picture of who someone has been.

So it goes with "Billy Joel: The Complete Albums Collection" ? a 15-CD (15!) collection that takes the Joel oeuvre from the dawn of the 1970s into the 21st century. From "Piano Man" to "Just the Way You Are" to "Uptown Girl" to "We Didn't Start the Fire" and beyond, it's quite a ride.

In recent years, Joel-bashing has become a not-uncommon exercise. He's saccharine, people say. Hackneyed. Not too relevant. Syrupy.

That's unfair. Joel is one of the premier pop songwriters of his generation, and even his more uneven efforts are generally good listening.

If you can ? and it's a lot to ask, true ? take the time to listen straight through to the more than 11 hours of music in these albums. Taken together, it's an epic portrait of an era and how it unfolded, in New York City and beyond.

Through music and words, we watch Joel move through Manhattan and Los Angeles of the 1970s, making sense of its darker corners and singing about weariness and struggle and odd characters, about moving away from hometown and high school and roots.

We see him pan with a wider lens in the 1980s, singing of joblessness in Allentown, the wages of Vietnam and the melancholy of starting to get old and remembering your first attempts at romance. We see him fall in love with Christie Brinkley and fall away from her. We see him start to age.

Along the way, we encounter frantic, high-speed odes to American history, wry perspectives on suburban sprawl, tributes to lobstermen, even a spate of classical music that's not completely memorable but utterly listenable. We are served up some outtakes. And, of course, we are offered love songs, lots of love songs: Love found, love lost, unexpected love, comfortable love, tortured love.

As the albums spin by and Joel's voice gets more gravelly, his life experiences are reflected in his songs. His has sometimes been a bumpy road, and many times he has worked through it with his craft. "I never felt the desire `til their music set me on fire," Billy Joel once sang. "And then I was saved." Whatever it was that set him on fire, we benefited across the decades ? as this sprawling, eye-opening collection vividly demonstrates.

? Ted Anthony, AP National Writer

___

"Tony Bennett -- The Complete Collection" (Columbia/RPM/Legacy)

This 73-CD, three-DVD collection, priced at around $400, reflects Tony Bennett's lifelong ambition to create a "hit catalog rather than hit records." It contains more than 1,000 individual songs recorded over more than six decades, from his first recording, a rare 1946 V-Disc with an Army band in Europe, to tunes from his first No. 1-charting album, "Duets II," released in September, pairing him with today's stars, including Lady Gaga and Carrie Underwood.

The consistent thread running through Bennett's career has been his determination to record good songs ? many from the "Great American Songbook" ? that wouldn't become obsolescent.

That hasn't always been easy. In the `50s ? as indicated on the six CDs with Bennett's Columbia singles ? the young singer often butted heads with producer Mitch Miller, who pushed him to croon often forgettable songs in a stiff operatic voice with choral groups and saccharine string arrangements. But Bennett's singing became more relaxed and jazzier once he began recording albums with more "Songbook" standards starting in 1955 with "Cloud 7."

Bennett's ability to blend pop with his jazz inclinations is what ultimately distinguishes him from his peers, and some of his best albums feature jazz greats. In the late `50s, he recorded "The Beat of My Heart" with Art Blakey, Jo Jones and other leading jazz drummers and became the first white vocalist to record with the Count Basie Orchestra.

Later, he made two memorable duet albums with the lyrical, impressionistic pianist Bill Evans for Fantasy during his 1972-86 hiatus from Columbia that followed perhaps his most ill-advised album, "Tony Sings the Great Hits of Today" (1970) with covers of songs by the Beatles and others.

There are more jazz treasures on two CDs filled with rarities and outtakes, including an exuberant duet with Frank Sinatra on "New York, New York." Of particular interest are two never-before-released albums: "On the Glory Road" (1962) and "Live At the Sahara: From This Moment On," documenting his 1964 Las Vegas debut.

The collection is augmented by three DVDs, including a rarely seen BBC show from 1971, "Tony Bennett Sings ... with The London Philharmonic Orchestra.

What's particularly noteworthy is that about a third of the collection has never before been released on CD ? and this collection gives Bennett the standing he deserves among the pantheon of American pop singers.

? Charles J. Gans, Associated Press

___

Sting, "Sting: 25 Years" (3 CDs, DVD) (A&M Records)

Sting's three-CD box set offers an intriguing portrait of the artist in his quarter-century quest to marry the many flavors of music. Bundling his early and later work together presents an excellent chance to really get a clear reading of how he has tweaked pop music and expanded its core.

His early solo compositions after leaving the Police veered largely toward jazz and world beats, and his first CD, "The Dream of the Blue Turtles" featured an impressive roster of jazz players: Branford Marsalis, Kenny Kirkland, Omar Hakim and Darryl Jones.

"If You Love Somebody Set Them Free" from that seminal 1985 album showcases Sting's flirtations for both jazz and rhythm and blues, while he revives the reggae that also influenced the Police in "Love Is the Seventh Wave," with its infectious refrain: "There is a deeper wave than this, rising in the land/There is a deeper wave than this, listen to me, girl."

World beats and jazz, of course, are offered up again and again over the years ? "Desert Rose," for example, from 1999's "Brand New Day," where Sting's vocals with Cheb Mami, share Middle Eastern inflections. "I Was Brought to My Senses," from 1996's "Mercury Rising," reflects just a taste of the Scottish Highland in its opening before floating to smooth jazz riffs.

Sting's musical explorations became even more interesting in 2003 with his "Sacred Love" album where Bach influenced "Whenever I Say Your Name," a song that had Mary J.. Blige on vocals. And there are tunes from his recent works, "Symphonicities," from 2010 and "If on a Winter's Night ..."

The boxed set comes with a nicely packaged book of writings and photos, and a DVD, and lyrics to each tune. Sting is an intelligent lyricist, which for some fans can be a turn-off. But like it or not, Sting's very complexities elevate his music, from the peppiness of "Brand New Day" to the edgy narrative "I Hung My Head" to the sweetness of "When We Dance."

Sting has truly given the gift of music.

_Dolores Barclay, AP National Writer

____

Wynton Marsalis, "Swinging Into the 21st" (Columbia/Legacy)

Over the past 30 years, Wynton Marsalis has gone from teenage trumpet prodigy to an institution unto himself. He's celebrating his 50th birthday with an 11-CD box set commemorating the monumental creative and stylistically diverse outburst that ushered in the millennium when he released nine albums between March 1999 and August 2000. The collection is capped off by one of his definitive works, the sacred composition "All Rise," recorded just days after 9/11. Only a player like Marsalis ? trumpeter, bandleader, arranger, composer and educator ? could have undertaken such a challenge.

Marsalis' trumpet virtuosity is on full display on the 11 and a half minute version of the standard "Cherokee" on one CD, which features selected highlights from his seven-CD "Live at the Village Vanguard" box set released in 2000. A relaxed Marsalis has fun playing with three different septet lineups ? including such outstanding players as pianist Marcus Roberts, alto saxophonist Wessell Anderson and trombonist Wycliffe Gordon ? performing both originals and standards at the iconic New York City jazz club from 1990-94.

As an educator, Marsalis continues his "Standard Time" album series paying respects to jazz giants on two CDs. His septet explores Thelonious Monk's repertoire in depth_ skipping some of the pianist's greatest hits like "`Round Midnight." On "Mr. Jelly Lord," Marsalis reinterprets the works of jazz's first major composer, Jelly Roll Morton, augmenting his band with several New Orleans veterans ? trombonist Lucien Barbarin, clarinetist Michael White, and Harry Connick Jr. (on piano on one track).

The collection also includes two diverse jazz scores for ballets; a never-used film score full of American roots music from blues and gospel to bluegrass intended for director John Singleton's "Rosewood"; his first contemporary classical string quartet, "At the Octoroon Balls," mixing jazz and folk motifs; and the chamber ensemble composition, "A Fiddler's Tale," an American adaptation of Igor Stravinsky's "L'Histoire du Soldat" that mixes in New Orleans jazz influences.

The problem is that in drawing from so many sources, Marsalis has not defined his own distinctive musical identity, and it's not clear whether his compositions will someday become part of the jazz canon. He is a masterful assimilator and adapter, but hasn't established himself as a major jazz innovator.

__ Charles J. Gans, Associated Press

___

Twisted Sister "From The Bars To The Stars: Three Decades Live" (Eagle Vision)

Twisted Sister is one of the most visual bands in the history of heavy metal, and this five-DVD box set chronicles their rise from New York bar band extraordinaire to worldwide metal legends, in all its cinematic glory.

The set includes their 1982 performance at Long Island, N.Y.'s Northstage Theater, and the 1982 coming-out show at England's Reading Festival, where the band won over a skeptical audience that began the afternoon by throwing garbage at them and ended up cheering them. It also includes the 2001 New York Steel benefit concert for the families of police officers and firefighters killed in the World Trade Center attacks, a show that reunited the band for the first time in 14 years.

In addition, there's "Live at Wacken," their 2003 festival show for a rabid German audience, and "A Twisted X-Mas," a video culled from three Christmas shows they did in December 2009 at the Las Vegas Hilton. This disc is the only one in the box set that hadn't previously been released. It begins with strippers pulling singer Dee Snider onto the stage on Santa's sleigh (hey, it's Vegas!) and includes numerous songs from their brilliant 2006 heavy metal Christmas album "A Twisted Christmas."

The box set also comes with some cool swag, including a silver Twisted Sister Christmas ornament, a vintage hot-pink band button from the 1970s, a laminated backstage pass from the New York Steel show, and a photocopy of the very first typed-out newsletter the band mailed to fans in 1979.

It's the definitive video history of one of the most underrated bands in heavy metal, drenched with band interviews and rehearsal footage (check out Snider grafting the vocals to the Doors' "Gloria" onto Twisted's "Shoot `Em Down" while guitarist Jay Jay French sings "Wild Thing" ? all at the same time). Moments like this are why God created box sets.

? Wayne Parry, AP Writer

___

Loudon Wainwright III, "40 Odd Years" (Shout! Factory)

The familiar shtick is captured repeatedly on a DVD included in this set: Loudon Wainwright III clenches his teeth, waggles his tongue, hops on one leg and sings with bracing humor, candor and power about the things he has seen and done. "My whole cheesy life," as he describes it in one of his best songs.

Wainwright makes his aural autobiography fascinating by mixing comedy and tragedy, with just enough of the latter to give his wit extra bite. Confessional songwriting seems to be a form of therapy for Wainwright, and after all these years, his willingness to share his story in self-deprecating detail remains astounding.

Four CDs are included with the DVD on "40 Odd Years," and while the title is marvelous, the material's just as good. Many of the performances here feature the troubadour solo as he offers insights about childbirth, childhood, parenthood, debauchery, divorce and death; about sex, guitars and roadkill; about family dysfunction, the joys of solitude and the ravages of time. There are also two references to dental floss.

Touted as the next Dylan, Wainwright instead became a one-of-a-kind artist. He arrived on the scene in the late 1960s fully formed, as evident in such early tunes as "Uptown." "I want to elevate up and down with you in the building of the Empire State," he sings. Now in his 60s, Wainwright remains prolific and has done some of his best work lately, including such songs as "Bed," "Surviving Twin" and "My Biggest Fan."

Wainwright has written so many gems that it was impossible to include them all here, but his essay in an accompanying 40-page booklet offers an eloquent apology for any omissions. The excellent liner notes make the set appealing even for longtime fans, as do a CD of rare and unreleased material and the terrific DVD, which includes documentaries, TV performances and lots of tongue-wagging.

? Steven Wine, Associated Press

____

Robert Johnson, "Robert Johnson: The Complete Original Masters. Centennial Edition" (Columbia/Legacy)

Pulling together a box set of recordings by Mississippi Delta blues legend Robert Johnson shouldn't be that tough a task. Johnson only released a handful of songs from two recording sessions in 1936 in 1937, in San Antonio, Texas and Dallas respectively.

But Johnson was no ordinary musician, and justly, Sony's Legacy division has treated his work with respect and detail. In the box set titled "Robert Johnson: The Complete Original Masters, Centennial Edition," homage is paid on 100th anniversary year of Johnson's birth with a dozen 78 rpm replicas of each of his released songs.

The set also contains two CDs of 42 master and alternate takes. For a retrospective of the times in which Johnson made his music, one of the CDs contains 10 songs from various artists recorded on the same days as the Robert Johnson sessions all those decades ago. There's a DVD documentary as well which takes a look at Johnson's short 27 years on Earth.

But to be clear, Johnson's vinyl is the centerpiece here. To hear the bluesman play classics like "Last Fair Deal Gone Down" and "Love In Vain Blues" on this medium is a treat. The slight crackle from those original recordings feels right at home between the newly etched grooves on a vinyl platter. Johnson deserves this analog attention, and not merely the 128 kbps stream of an MP3 on an iPod.

For the re-mastering of the vinyl records themselves, Sony turned to 78 rpm format expert Harry Coster, who keeps a record press in a Netherlands barn and handmade new polystyrene pressings especially for this effort.

Johnson is one of the most important American artists ever recorded. Thus, this sort of packaged adoration seems fitting for a young man who influenced so many.

? Ron Harris, Associated Press

___

Various Artists, "Fifteen Minutes" (Legacy Recordings)

"Fifteen Minutes," crafted as an audio and artistic homage to Andy Warhol, is certainly tailored for a small audience.

First of all, the initial run was limited to 1,964 copies. And at $600 a pop, for just three compact discs, four vinyl records and 16 lithograph prints, it's no bargain. But for those with even more refined tastes, there's the $20,000 deluxe edition of just 85 copies featuring numbered silkscreens.

Ahem.

So, is it worth it?

The concept was to have artists who either worked with or were influenced by Warhol to contribute both a work of art and an audio recording, which take the form of either music, poetry or spoken word.

Some of the contributions are, frankly, unlistenable.

One entire 40-minute disc consists of Vincent Fremont, a filmmaker in Warhol's inner circle, interviewing Brigid Berlin, a New York socialite, artist and central part of Warhol's entourage who acted in some of his films. The conversation has its moments of insight and interest, but except for hardcore Warhol devotees, it's hard to imagine how it would warrant more than one listen.

While at least some thought went into that submission, Bob Dylan's contribution is just a retread of his original recording of "When I Paint My Masterpiece."

The entire project was assembled by Jeff Gordon, a Warhol associate and artist, and painter Path Soong to correspond with what would have been Warhol's 83rd birthday.

Given its high price and exclusivity, "Fifteen Minutes" was clearly created with a small audience in mind. Members of that club may be more than willing to drop the money to get it, but general audiences need not worry too much about what they're missing.

? Scott Bauer, Associated Press

___

Grateful Dead, "Europe `72: The Complete Recordings" (Rhino)

How much is too much when it comes to the Grateful Dead?

That question is being tested like never before with the 73-disc box set "Europe `72."

For the venerable band's detractors, even more than a couple minutes of jamming sends them running for the exits.

But to Deadheads who started trading shows on tape 40 years ago and continue to snatch up archival releases from the vault, there appears to be a bottomless desire for more.

"Europe `72," which includes all 25 shows from their revered 1972 tour of Europe, is the boldest release to date.

It's a lot of Dead, to be sure.

The 25 shows amount to 73 discs, more than 70 hours of music. And at $450 the price isn't chump change, either. Although, when priced out it comes to just $6.25 per disc.

The box set was originally offered in a limited numbered run of 7,200 in a replica travel trunk, complete with a hardcover book. After those sold out, the music-only version of the set was put up for sale. Those unwilling to take the tour from Copenhagen to Amsterdam and all stops in between can also buy individual shows.

But for those with the cash, the entire tour is something to behold. In typical Dead fashion, every show is unique and some are better than others. Only one song ? "Mr. Charlie" ? showed up every night.

In general, the Dead is in prime form while in a period of transition. Original keyboardist Ron "Pigpen" McKernan was ill but still performing, while his eventual replacement Keith Godchaux was already on board along with his wife, backup vocalist Donna Jean Godchaux.

The tour was first immortalized on the band's famous three-record live set "Europe `72," released at the end of 1972. But until now, only one complete show from the tour had ever seen the light of day.

Now it's all there for whoever is willing to take it on.

? Scott Bauer, Associated Press

Source: http://us.rd.yahoo.com/dailynews/rss/music/*http%3A//news.yahoo.com/s/ap/20111123/ap_en_mu/us_sound_bites_box_sets

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Dhoni rested, Sehwag to lead India in ODIs (Reuters)

MUMBAI (Reuters) ? India have rested captain Mahendra Singh Dhoni and named opener Virender Sehwag as skipper for the five-match one-day series against West Indies starting next week.

Sachin Tendulkar, who still needs one more century to complete 100 international hundreds, has been rested for the first three matches, BCCI secretary Sanjay Jagdale said in a statement on Friday.

"Yuvraj Singh was not considered for selection as he has informed us that he is not fully fit," Jagdale added.

Cuttack hosts the first one-dayer on Nov. 29, followed by matches in Visakhapatnam (Dec. 2), Ahmedabad (Dec. 5), Indore (Dec. 8) and Chennai (Dec. 11).

India squad: Virender Sehwag (captain), Gautam Gambhir, Virat Kohli, Ajinkya Rahane, Suresh Raina, Ravindra Jadeja, Parthiv Patel, Ravichandran Ashwin, Praveen Kumar, R. Vinay Kumar, Umesh Yadav, Varun Aaron, Rohit Sharma, Manoj Tiwary, Rahul Sharma.

(Reporting by Amlan Chakraborty in New Delhi; Editing by John Mehaffey. To query or comment on this story email sportsfeedback@thomsonreuters.com)

Source: http://us.rd.yahoo.com/dailynews/rss/india/*http%3A//news.yahoo.com/s/nm/20111125/india_nm/india607334

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Thursday, November 24, 2011

Medvedev: Russia may target US missile shield (AP)

MOSCOW ? Russia threatened on Wednesday to deploy missiles to target the U.S. missile shield in Europe if Washington fails to assuage Moscow's concerns about its plans, a harsh warning that reflected deep cracks in U.S.-Russian ties despite President Barack Obama's efforts to "reset" relations with the Kremlin.

President Dmitry Medvedev said he still hopes for a deal with the U.S. on missile defense, but he strongly accused Washington and its NATO allies of ignoring Russia's worries. He said Russia will have to take military countermeasures if the U.S. continues to build the shield without legal guarantees that it will not be aimed against Russia.

The U.S. has repeatedly assured Russia that its proposed missile defense system wouldn't be directed against Russia's nuclear forces, and it did that again Wednesday.

"I do think it's worth reiterating that the European missile defense system that we've been working very hard on with our allies and with Russia over the last few years is not aimed at Russia," said Capt. John Kirby, a Pentagon spokesman. "It is ... designed to help deter and defeat the ballistic missile threat to Europe and to our allies from Iran."

White House spokesman Tommy Vietor said the United States will continue to seek Moscow's cooperation, but it must realize "that the missile defense systems planned for deployment in Europe do not and cannot threaten Russia's strategic deterrent."

But Medvedev said Moscow will not be satisfied by simple declarations and wants a binding agreement. He said, "When we propose to put in on paper in the form of precise and clear legal obligations, we hear a strong refusal."

Medvedev warned that Russia will station missiles in its westernmost Kaliningrad region and other areas, if the U.S. continues its plans without offering firm and specific pledges that the shield isn't directed at its nuclear forces. He didn't say whether the missiles would carry conventional or nuclear warheads.

In Brussels, NATO Secretary-General Anders Fogh Rasmussen said he was "very disappointed" with Russia's threat to deploy missiles near alliance nations, adding that "would be reminiscent of the past and ... inconsistent with the strategic relations NATO and Russia have agreed they seek."

"Cooperation, not confrontation, is the way ahead," Rasmussen said in a statement.

The U.S. missile defense dispute has long tarnished ties between Moscow and Washington. The Obama administration has repeatedly said the shield is needed to fend off a potential threat from Iran, but Russia fears that it could erode the deterrent potential of its nuclear forces.

"If our partners tackle the issue of taking our legitimate security interests into account in an honest and responsible way, I'm sure we will be able to come to an agreement," Medvedev said. "But if they propose that we `cooperate,' or, to say it honestly, work against our own interests, we won't be able to reach common ground."

Moscow has agreed to consider a proposal NATO made last fall to cooperate on the missile shield, but the talks have been deadlocked over how the system should be operated. Russia has insisted that it should be run jointly, which NATO has rejected.

Medvedev also warned that Moscow may opt out of the New START arms control deal with the United States and halt other arms control talks, if the U.S. proceeds with the missile shield without meeting Russia's demand. The Americans had hoped that the START treaty would stimulate progress in further ambitious arms control efforts, but such talks have stalled because of tension over the missile plan.

While the New START doesn't prevent the U.S. from building new missile defense systems, Russia has said it could withdraw from the treaty if it feels threatened by such a system in future.

Medvedev reaffirmed that warning Wednesday, saying that Russia may opt out of the treaty because of an "inalienable link between strategic offensive and defensive weapons."

The New START has been a key achievement of Obama's policy of improving relations with Moscow, which had suffered badly under the George W. Bush administration.

"It's impossible to do a reset using old software, it's necessary to develop a new one," Medvedev's envoy to NATO, Dmitry Rogozin, said at a news conference.

The U.S. plan calls for placing land- and sea-based radars and interceptors in European locations, including Romania and Poland, over the next decade and upgrading them over time.

Medvedev said that Russia will carefully watch the development of the U.S. shield and take countermeasures if Washington continues to ignore Russia's concerns. He warned that Moscow would deploy short-range Iskander missiles in Kaliningrad, a Baltic Sea region bordering Poland, and place weapons in other areas in Russia's west and south to target U.S. missile defense sites. Medvedev said Russia would put a new early warning radar in Kaliningrad.

He said that as part of its response Russia would also equip its intercontinental nuclear missiles with systems that would allow them to penetrate prospective missile defenses and would develop ways to knock down the missile shield's control and information facilities.

Igor Korotchenko, a Moscow-based military expert, was quoted by the state RIA Novosti news agency as saying that the latter would mean targeting missile defense radars and command structures with missiles and bombers. "That will make the entire system useless," he said.

Medvedev and other Russian leaders have made similar threats in the past, and the latest statement appears to be aimed at the domestic audience ahead of Dec. 4 parliamentary elections.

Medvedev, who is set to step down to allow Prime Minister Vladimir Putin to reclaim the presidency in March's election, leads the ruling United Russia party list in the parliamentary vote. A stern warning to the U.S. and NATO issued by Medvedev seems to be directed at rallying nationalist votes in the polls.

Rogozin, Russia's NATO envoy, said the Kremlin won't follow the example of Soviet President Mikhail Gorbachev and take unwritten promises from the West.

"The current political leadership can't act like Gorbachev, and it wants written obligations secured by ratification documents," Rogozin said.

Medvedev's statement was intended to encourage the U.S. and NATO to take Russia seriously at the missile defense talks, Rogozin said. He added that the Russian negotiators were annoyed by the U.S. "openly lying" about its missile defense plans.

"We won't allow them to treat us like fools," he said. "Nuclear deterrent forces aren't a joke."

____

Associated Press writers Nataliya Vasilyeva in Moscow, Pauline Jelinek and Julie Pace in Washington and Slobodan Lekic in Brussels contributed to this report.

Source: http://us.rd.yahoo.com/dailynews/rss/world/*http%3A//news.yahoo.com/s/ap/20111124/ap_on_re_eu/eu_russia_missile_defense

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Apollo Hospitals to launch 100 diabetes-treatment clinics (Reuters)

MUMBAI (Reuters) ? Apollo Hospitals Enterprise said on Wednesday it plans to launch 100 clinics dedicated to treat diabetes across India in three months.

The clinics would work on a specifically developed clinical pathway and offer standardised care to the diabetic patients, it said in a statement.

"Keeping in mind the rising burden of diabetes, India would need an integrated framework that would enable diabetics manage their lifestyle better," Chairman Prathap Reddy was quoted as saying in the statement.

(Reporting by Kaustubh Kulkarni in Mumbai)

Source: http://us.rd.yahoo.com/dailynews/rss/india/*http%3A//news.yahoo.com/s/nm/20111123/india_nm/india606844

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Latest developments in the Occupy protests (AP)

UNITED STATES

During the first two months of the nationwide Occupy protests, the movement that is demanding more out of the wealthiest Americans cost local taxpayers at least $13 million in police overtime and other municipal services, according to a survey by The Associated Press.

The heaviest financial burden has fallen upon law enforcement agencies tasked with monitoring marches and evicting protesters from outdoor camps. And the steepest costs by far piled up in New York City and Oakland, Calif., where police clashed with protesters on several occasions.

The AP gathered figures from government agencies in 18 cities with active protests and focused on costs through Nov. 15, the day protesters were evicted from New York City's Zuccotti Park, where the protests began Sept. 17 before spreading nationwide. The survey did not attempt to tally the price of all protests but provides a glimpse of costs to cities large and small.

Broken down city by city, the numbers are more or less in line with the cost of policing major public events and emergencies. In Los Angeles, for example, the Michael Jackson memorial concert cost the city $1.4 million. And Atlanta spent several million dollars after a major snow and ice storm this year.

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Protesters want shoppers to occupy something besides door-buster sales and crowded mall parking lots on Black Friday.

Some don't want people to shop at all. Others just want to divert shoppers from big chains and giant shopping malls to local mom-and-pops. And while the actions don't appear coordinated, they have similar themes: supporting small businesses while criticizing the day's dedication to conspicuous consumption and the shopping frenzy that fuels big corporations.

Nearly each one promises some kind of surprise action on the day after Thanksgiving, the traditional start of the holiday shopping season.

Some business experts note that trying to shop exclusively local neglects economies of scale, job specialization and other benefits that big, multi-state corporations can bring. They also say small businesses aren't necessarily better employers in terms of wages, benefits, opportunities for advancement and other measures.

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Occupy Wall Street has a benefit album planned with Jackson Browne, Third Eye Blind, Crosby & Nash, Devo, Lucinda Williams and even some of those drummers who kept an incessant beat at Manhattan's Zuccotti Park.

Participants in the protest movement said Wednesday that "Occupy This Album," which will be available sometime this winter, will also feature DJ Logic, Ladytron, Warren Haynes, Toots and the Maytals, Mike Limbaud, Aeroplane Pageant, Yo La Tengo and others.

Activist filmmaker Michael Moore is also planning to sing.

Jason Samel, a musician who is putting together the disc, said the goal is to raise $1 million to $2 million to help fuel the movement.

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NEW YORK

The New York Police Department's commissioner on Wednesday sent an internal message to officers ordering them not to unreasonably interfere with media access during news coverage and warning those who do will be subject to disciplinary action, after several journalists were arrested covering Occupy Wall Street demonstrations last week.

A reporter and a photographer with The Associated Press were among those arrested while on private property covering a rally by protesters Nov. 15 in Manhattan. Police made the arrests after the demonstrators clipped a chain-link fence and entered a vacant lot owned by a nearby church.

The police department message notes that officers should not restrict media access on private property "to the extent it is feasible to do so."

A coalition of media outlets, including the AP, sent police a letter protesting the treatment after at least half a dozen journalists were arrested. The media also argued police wrongly blocked reporters from seeing when authorities cleared out the Occupy camp in lower Manhattan's Zuccotti Park. The letter suggested the police roughed up some journalists.

Commissioner Raymond Kelly's letter makes clear that journalists are entitled to cross police and fire lines, unless it is unsafe or a live crime scene, and officers have a duty to provide access and information to the extent they can.

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CALIFORNIA

The first female chancellor of the University of California, Davis, has found herself in the middle of a national debate over police use of pepper spray to subdue protesters and the way colleges balance free speech and public safety.

Linda Katehi, 57, has come under intense pressure after viral online videos showed police officers dousing a row of protesters with pepper spray as they sat passively on the ground with their arms linked.

Eleven students were hit by pepper spray, including two who were treated at a hospital and later released, university officials said.

Katehi has placed the campus police chief and two pepper-spraying officers on administrative leave. She also asked prosecutors to drop charges against nine students who were arrested and said the school would reimburse students for medical expenses.

She has publicly said she was horrified when she watched the videos. Even so, she is fighting calls for her resignation.

Occupy UC Davis protesters, meanwhile, have ignored a camping ban. The encampment went back up Monday night, and campus officials said it included as many as 80 tents Wednesday.

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MICHIGAN

Dozens of people linked to the Occupy Wall Street movement have held a protest at the offices of U.S. Rep. Fred Upton.

The Republican was among 12 lawmakers on the Joint Select Committee on Deficit Reduction that failed to reach agreement by Wednesday's deadline.

WSJM-AM says 30 to 40 people from Occupy Southwest Michigan demonstrated Wednesday in St. Joseph, Upton's hometown.

The protesters say they oppose America's growing income inequality and Upton's economic policies.

Leo Javonovic says Upton is "part of the gridlock" in Washington and a defender of the interests of the wealthiest 1 percent of Americans.

In an opinion article in the Kalamazoo Gazette, Upton says good ideas for fundamental change emerged from the committee. He says they could bear fruit down the road.

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MINNESOTA

Anti-Wall Street protesters in Minneapolis will be able to affix signs and posters to the plaza outside the Hennepin County Government Center but cannot use tents or sleep on the plaza, a federal judge ruled Wednesday.

The protesters argued that the county's rules against having tents, using electricity, writing with chalk, or posting signs were unconstitutional and violated their free speech rights.

But except for the ban on posting signs, Senior U.S. District Judge Richard Kyle sided with the county, saying the restrictions were reasonable. The judge granted the protesters' request to block the county from enforcing the ban on posting signs but denied their other requests.

Kyle also ordered both sides into settlement talks. He noted that the protesters, who have been at the downtown Minneapolis plaza since Oct. 7, were unlikely to leave anytime soon and that the county has recognized that the demonstrators may assemble in the plaza "during any hour of the day."

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LONDON

The City of London corporation took a step Wednesday to evict protesters camped outside St. Paul's Cathedral, insisting in court that the issue is not about protecting banks but protecting the rights and freedoms of others.

The organization ? which controls the area around St. Paul's ? says the ongoing Occupy London protest camp is harming nearby businesses. It also says protesters are drinking late into the night and creating an unpleasant atmosphere. It wants Britain's High Court to issue an eviction notice to force the protesters to move.

Protesters have camped outside St. Paul's since mid-October and say they will fight any legal bid to evict them.

Their proximity to Christopher Wren's 300-year-old icon has embroiled the church in a conflict between bank-bashing protesters and the city's finance industry. The church's position on the protesters has shifted several times, and the cathedral's dean and a senior priest have both resigned over the crisis.

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SOUTH CAROLINA

Several Occupy Columbia protesters arrested last week for refusing to leave the Statehouse grounds sued South Carolina Gov. Nikki Haley and state public safety officials, saying their First Amendment rights were trampled when they were arrested for demonstrating on public property.

The suit alleges that Haley blames the protesters for damage to Statehouse grounds because she doesn't agree with their message. A spokesman for the Department of Public Safety had no comment, and Rob Godfrey, a spokesman for Haley, said the governor would fight the lawsuit.

The seven people who brought suit were among 19 protesters arrested Nov. 16 after Haley said anyone attempting to camp out on the Statehouse grounds after 6 p.m. would be arrested for trespassing.

Source: http://us.rd.yahoo.com/dailynews/rss/us/*http%3A//news.yahoo.com/s/ap/20111124/ap_on_re_us/us_occupy_glance

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